Possible Leukemia Causes and Risk Factors

Leukemia is a disease that is considered to be life-threatening. It requires prompt intervention when discovered, in order to maximize the chances of recovering through specific treatment and therapy. Leukemia is basically a type of cancer of the bone marrow and blood, caused by inappropriate cellular activity. The disease can be of different forms, according to the types of blood cells that cause its development. Also, if leukemia is developing rapidly, it is called acute leukemia, while if the disease is developing slowly, it is referred to as chronic leukemia.

The direct leukemia causes are still unknown. In present, medical science isn’t able to establish the specific leukemia causes. However, a strong connection between certain genetic factors and the development of the disease has been revealed. Leukemia occurs on the background of genetic failure that causes the excessive production of incomplete, partially matured blood cells. Also, leukemia has a hereditary character, allowing the transmission of genetic predispositions to disease from one generation to another. Although many factors are known to contribute to the development of leukemia, they alone can’t be considered leukemia causes.

Despite the fact that statistics indicate a higher incidence of the disease in people that are exposed to some environmental factors of risk, leukemia doesn’t seem to be caused by neither of them in particular. Among the environmental factors that are thought to be leukemia causes, here are some of the most plausible ones:

- Smoking – smoking is thought to increase the chances of being affected by leukemia. Although statistics show that around 20 percent of acute leukemia cases are related to smoking, leukemia also occurs to people that don’t smoke and therefore it can’t be considered a leukemia cause on itself;

- Prolonged exposure to radiation – Radiation is considered to facilitate the development of leukemia. It is believed that exposure to X-rays can be a leukemia cause;

- Prolonged exposure to benzene – statistics reveal that this is a major factor of risk in some forms of leukemia, such as myelogenous leukemia;

- Chemotherapy and cancer treatment – previous cancer treatments and chemotherapy are known to facilitate the occurrence and development of leukemia and can be considered plausible leukemia causes. Within a few years from the completion of chemotherapy and other treatments for certain forms of cancer, most people can develop leukemia.

Among the genetic factors that are considered to be leukemia causes, the following ones are thought to be the most important:

- chromosome abnormalities – some rare genetic syndromes are known to contribute to leukemia causes;

- Immune system genetic problems - a weak immune system is very likely to facilitate the occurrence of leukemia and therefore can be considered a leukemia cause;

- Down syndrome – children born with this syndrome have a very high risk of developing acute leukemia.

The list of possible leukemia causes can continue further, but these are the most common factors that are considered to be interrelated with leukemia. While some of them can be prevented, others reside within the genes and in present can’t be corrected. In future, however, thanks to medical advance, we will probably be able to prevent leukemia and other forms of cancer.

General Aspects of Leukemia

General Aspects of Leukemia - Many people suffer from leukemia these days. A large number of cases of cancer are identified to be leukemia. Leukemia is a sort of cancer of the blood and marrow. The disease is characterized through the overproducing of immature blood cells (stem cells) that aren’t able to fully develop and to carry out the activities of normal blood cells.

According to their functions and structure, there are three different types of cells within the normal blood: red blood cells, white blood cells and platelets. Through the process of hematopoiesis, these three types of blood cells are developed from a distinctive type of blood cell called stem cell. Stem cells divide and go through several stages of development to finally form a mature blood cell of a particular type, with a certain, distinctive function in the body. The process through which a stem cell morphs into a mature blood cell takes place within the bone marrow.

According to the speed of development and the persistence of the disorder, there are two types of leukemia: acute leukemia and chronic leukemia. Acute leukemia is known to develop very rapidly, while chronic leukemia is developed slowly. According to the types of blood cells affected by the disease, leukemia can either be lymphocytic or myelogenous.

Lymphocytic and myelogenous types of leukemia are developed from different types of cells: the lymphocytic type of leukemia develops from cells called lymphoblasts or lymphocytes in the spongious tissue of the bones, while the myelogenous type of leukemia (sometimes refered to as myeloid and myelocytic leukemia) develops from myeloid cells.

In the case of acute forms of leukemia, the abnormal cells come from early, immature cells. Such forms of the disorder have a very fast rate of development, due to the fact that normal stem cells tend to multiply frequently. Leukemia cells usually don’t divide faster and more frequently than normal stem cells, they simply don’t stop their process of division when they should. Sometimes the numbers of white blood cells are very high, while in other cases they can be normal or low.

Chronic leukemia, apart from its slow development, is different from acute leukemia by the level of maturation that the diseased cells are able to reach. Stem cells affected by chronic leukemia reach a higher level of maturation but they present abnormalities and they can’t act as healthy white blood cells do. Unlike acute leukemia, in the chronic form of the disease the unhealthy cells have much longer periods of life and they tend to accumulate in different parts of the body.

Leukemia affects people of all age groups. While children usually respond better to the treatment for leukemia and sometimes deal well with the disease, adults difficultly cope with this form of cancer.

Regardless of age and sex, many people are diagnosed with forms of leukemia. Children tend to respond better to some types of leukemia, while adults difficultly cope with the disease. The cases of acute leukemia exceed those of chronic leukemia by approximately 10 percent. Older adults seem to be affected the most by acute leukemia. Around two thirds of acute leukemia cases seem to occur after the age of 60.

Understanding Chronic Leukemia

Leukemia is a disease of the blood and bone marrow that occurs on the background of genetic predispositions to cancer.causes and symptoms of leukemia you have to know, Leukemia affects the cellular process of maturation, causing the accumulation of immature blood cells in the spinal marrow and bloodstream. In some cases leukemia causes the incomplete cells to multiply very quickly, while in other cases the abnormal blood cells have prolonged periods of life and persist in different places inside the body. Incomplete blood cells can’t substitute for normal blood cells, as they can’t carry out their roles. The cells affected by leukemia are therefore incompatible with the organism and can cause serious damage.

Judging by the speed of development and the persistence of the disorder, there are two types of leukemia: acute leukemia and chronic leukemia. Judging by the types of stem cells affected by the disorder, leukemia can either be lymphocytic or myelogenous.

Acute leukemia is different from chronic leukemia by the levels that stem cells are able to reach in their development (stem cells that present anomalies still manage to partially develop and either resemble immature cells or complete, normal white blood cells).

Acute leukemia is a form of cancer that develops very rapidly. It is manifested through overpopulation of the blood with immature cells that are unable to fulfill the functions of normal blood cells. In the case of acute leukemia, the marrow is unable to produce normal quantities of red blood cells, white blood cells and platelets. Patients who suffer from leukemia also develop anemia, a deficiency of normal red blood cells. Also, a decreased number of white blood cells reduces the body’s ability of overcoming infections, while the lack of platelets facilitates inflammation and bleeding.

Chronic leukemia tends to develop slower than acute leukemia. In the case of chronic leukemia, the body is able to produce blood cells that are more mature than those produced in acute leukemia. Although these cells may appear incomplete, they can’t fulfill their roles inside the organism and tend to cluster at different levels of the body. They also have a longer period of life.

Chronic leukemia of lymphocytic form is known to affect a type of blood cell called B lymphocyte. The disease weakens the immune system, interferes in the normal activity of the spinal marrow and facilitates the access of harmful cells to body organs. Chronic lymphocytic leukemia first occurs at the levels of the bone marrow, but can quickly spread to different organs and tissue through the bloodstream.

The presence of chronic lymphocytic leukemia is usually revealed by blood tests and careful body examination. Although apparently some people may have no symptoms of the disease, other patients may experience fatigue, lack of concentration, poor balance, memory loss, deterioration of vision and hearing, vertigos, body weakness, joint and bone pains. Just like in other forms of the disease, chronic leukemia requires immediate specific treatment and therapy. The chances of fully overcoming the disease are considerably enhanced if it is discovered quickly.

Causes and Symptoms of Leukemia

The word leukemia is derived from two Greek words when combined together means white blood. Leukemia is the cancer of the blood or the bone marrow and can be classified in two types:

Acute Leukemia:

This type of leukemia occurs where DNA of immature blood is damaged. This results in the immature blood cells growing disorderly. Blood cells die all the while and are replaced by new blood cells which the bone marrow produces. However, abnormal blood cells do not die quickly and quickly crowd out the newer blood cells. It is this crowding out that makes the patient ill. Acute leukemia mostly affects children.

Acute leukemia can further be subdivided into Acute Lymphocytic Leukemia (ALL) and Acute Myelogenous Leukemia (AML)

Chronic Leukemia:

This is the rapid build up of mature but abnormal blood cells. Note that acute leukemia focuses on immature blood cells, chronic leukemia focuses on mature blood cells. This mostly affects older people and does not require immediate action compared to those suffering from acute leukemia.

Chronic leukemia can further be subdivided into Chronic Myelogenous Leukemia (CML) and Chronic Lymphocytic Leukemia (CLL)

Symptoms of leukemia are:

1. Poor Blood clotting

The clotting of the blood will be poor. This is because the new blood cells which are essential in the clotting process are being crowded out. This will make the sufferer bruise quite easily or bleed excessively. Sufferer may develop petechiae which are pinprick bleeds.

2. Suppressed immune system.

Since the normal blood cells have been suppressed or crowded out by the abnormal blood cells, the immune system of the body will be compromised. Note that the body’s immune system is built around the normal white blood cells. The results in the sufferer becoming prone to many opportunistic infections

3. Anemia
Due to insufficient amounts of healthy blood cells in the body system, the patient will develop anemia. Symptoms of this are pale skin and difficulty with breathing.

4. Other symptoms of leukemia are nausea, fatigue, headaches or the feeling of fullness caused by an inflated spleen or liver.

If you notice any of the above symptoms of leukemia, it is advisable you seek help fast.

Alternative Therapy and Complimentary Medicine for Leukemia

I recently learned that the daughter of a friend with T-cell acute lymphoblastic leukemia was diagnosed. My recent research on the treatment of complementary and alternative medicine has shown me that the chemotherapy is prescribed in the rule to leukemia actually weakens the immune system.
Immediately I began to supplement therapy and research on alternative medicine, natural medicine, that my friend can use with conventional chemotherapy recommended by your doctor.

Alternative Therapy and complementary medicine for leukemia, focusing on strengthening the immune system. Both leukemia and conventional treatments that weaken the immune system. Complementary medicine taken in combination with conventional therapy, the patients immune system to fight the power, to the disease. Alternative therapy in the form of free medicines to contribute as below also help kill cancer cells and prevents the formation of new lists.

Complimentary Medicine for Leukemia:

Diet

Fruits, vegetables, whole grains, nuts and other legumes contain the antioxidants and other nutrients needed to fight free radicals that cause cancer and destroy the immune system. All these foods contain the highest concentration of antioxidants available. Raw foods also work to flush toxins from the body so it can better fight the leukemia.


Complimentary Medicine for Leukemia: Vitamin A
A recent study showed Vitamin A to be 33% effective in curing leukemia even without chemotherapy. This percentage may not seem high until compared with the success rate of chemotherapy on most cancers, which is a mere 2%.